Independent · Self-funded · Open data
The biology of a peritoneal-flap neovagina, documented one body at a time.
Independent, self-funded research by Erica C Morton on the tissue biology, microbiome, and hormonal behavior of peritoneal-derived neovaginal anatomy. The design is single-subject: N = 1, where I am both the investigator and the only subject.
01 — Research program
The studies
Active
Neovaginal microbiome establishment
Can peritoneal-derived tissue establish and hold a Lactobacillus-majority microbiome under sustained estrogenization and probiotic loading?
Read overviewClosed
Cyclical hormone protocol
Pharmacokinetic documentation of a 28-day cyclical estradiol & progesterone protocol. Closed after a confound; PK data preserved as a complete descriptive dataset.
Read overview02 — Writing
Recent writing
Why N = 1, and why publish itA single-subject design can’t tell you what is true of a population. It can tell you, in unusual detail, what happened in one body — and that has its own kind of value.What the surgical literature leaves outThere is a reasonable body of work on how peritoneal-flap neovaginoplasty goes. There is very little on what the tissue does afterward — and that gap is the reason this program exists.Doing science without an institutionNo grant, no department, no ethics board reading over my shoulder. That changes what I’m free to study — and it changes what I owe in return.
03 — Record
Protocols and raw data are public.
Every study is pre-registered before measurement and its raw data published. Identity, registrations, and datasets live on permanent third-party records.